Sensitivity Study of the Dynamics of Three-Phase Photovoltaic Inverters With an LCL Grid Filter

[EN] An accurate small-signal model of three-phase photovoltaic (PV) inverters with a high-order grid filter is derived in this paper. The proposed model takes into account the influence of both the inverter operating point and the PV panel characteristics on the inverter dynamic response. A sensitivity study of the control loops to variations of the dc voltage, PV panel transconductance, supplied power, and grid inductance is performed using the proposed small-signal model. Analytical and experimental results carried out on a 100-kW PV inverter are presented.Figueres Amorós, E.; Garcerá, G.; Sandia Paredes, J.; González Espín, FJ.; Calvo Rubio, J. (2009). Sensitivity Study of the Dynamics of Three-Phase Photovoltaic Inverters With an LCL Grid Filter. IEEE Transactions on Industrial Electronics. 56(3):706-717. doi:10.1109/TIE.2008.2010175S70671756

Aplicación del modelo Flipped Classroom y las TIC en las asignaturas de la materia de Ciencias Biológicas del Grado en Ciencias de la Actividad Física y del Deporte.

El presente proyecto pretende mejorar la calidad docente y, por ende, mejorar los resultados académicos de las asignaturas que forman la Materia de Ciencias Biológicas (Anatomía Humana, Fisiología del Deporte y Biomecánica del Deporte), encuadradas dentro del Módulo de Ciencias Básicas y contempladas en la estructura del Grado en Ciencias de la Actividad Física y del Deporte, según su memoria aprobada en el 2009 (Resolución de 13 de noviembre de 2009, pag. 732) y verificada en febrero de 2016 (expediente Nº: 1250/2009 ID título: 2500909). Cabe destacar que las asignaturas de la Materia están consideradas como créditos de Formación Básica y son impartidas en primer y segundo curso de la titulación, teniendo una carga crediticia total de 16 créditos ECTS. Para ello, el presente proyecto pretende utilizar las Tecnologías de la Información y de la Comunicación (TIC) junto con un nuevo abordaje educativo denominado Flipped Classroom (FC), como medios para mejorar y facilitar la adquisición de las competencias clave de las asignaturas que comprenden la Materia de Ciencias Biológicas. Para el desarrollo del proyecto, se pretende generar video-tutoriales, que se pondrán a disposición de los alumnos previamente a las clases teóricas en aula con la intención de involucrar a los alumnos en el proceso de aprendizaje. Igualmente, se diseñarán herramientas de autoevaluación de los contenidos visualizados por los alumnos.Actividad Física y Deport

Contaminación lumínica en España 2010

A partir de imágenes nocturnas entre 1992 y 2007 de los satélites DMPS se ha obtenido una evolución por provincia del aumento de la emisión al luz espacio causante de la contaminación lumínica en España. El crecimiento medio nacional es del 54% en el periodo de estudio. Con los datos de INE y MITyC estimamos que el consumo nacional en alumbrado público es de 5.4 ±0.1 Twh/año a fecha de 2007. El objetivo nacional de consumo en alumbrado público anual es de 75 kwh por habitante. Sin embargo a partir de los datos oficiales calculamos que la media nacional está en 118 kwh por habitante en el año 2007 y crece

Prevalence and Distribution of High-Risk Genotypes of HPV in Women with Severe Cervical Lesions in Madrid, Spain: Importance of Detecting Genotype 16 and Other High-Risk Genotypes

Background. Persistent infection with high-risk human papillomavirus (HR-HPV) has been demonstrated to be the necessary causal factor for developing cervical cancer. To know the most prevalent HR-HPV in different geographical areas is important to design diagnostic tests and implementation of vaccines. Objectives. The goal of this study is to evaluate the prevalence of HR-HPV in a total of 1001 patients, 198 with normal cytology results, 498 with low-grade squamous intraepithelial lesion (LSIL), and 205 with high-grade squamous intraepithelial lesion (HSIL) who attended our gynaecology department for opportunistic screening of HPV infection. Study design. Cervical samples were taken in a PreservCyt vial (Cytyc Corporation, Boxborough, MA). Hybrid capture assay was carried out following the manufacturer's instructions (Digene Corp., Gaithersburg, MD). All samples were further studied with polymerase chain reaction (PCR) (Linear Array HPV Genotyping Test, Roche Diagnostics, Mannheim, Germany). Results. Genotype 16 was the most prevalent HR-HPV in the three groups, 17.8% in the patients with normal cytology results, 22.3% in the LSIL group, and 60% in the HSIL group. Genotype 18 had a very low prevalence in all groups. Other HR-HPV genotypes such as genotype 31, genotype 58 and genotype 52 were found in significant numbers in HSIL patients. Discussion. Our data show that genotypes 16, 31, 58, and 52 are the most prevalent HR-HPV in cervical samples with severe intraepithelial lesion in Spain. There may be some geographical variation in prevalence of carcinogenic types, and it must be considered for designing diagnostic tests and vaccine

Prevalence and Distribution of High-Risk Genotypes of HPV in Women with Severe Cervical Lesions in Madrid, Spain: Importance of Detecting Genotype 16 and Other High-Risk Genotypes

Background. Persistent infection with high-risk human papillomavirus (HR-HPV) has been demonstrated to be the necessary causal factor for developing cervical cancer. To know the most prevalent HR-HPV in different geographical areas is important to design diagnostic tests and implementation of vaccines. Objectives. The goal of this study is to evaluate the prevalence of HR-HPV in a total of 1001 patients, 198 with normal cytology results, 498 with low-grade squamous intraepithelial lesion (LSIL), and 205 with high-grade squamous intraepithelial lesion (HSIL) who attended our gynaecology department for opportunistic screening of HPV infection. Study design. Cervical samples were taken in a PreservCyt vial (Cytyc Corporation, Boxborough, MA). Hybrid capture assay was carried out following the manufacturer's instructions (Digene Corp., Gaithersburg, MD). All samples were further studied with polymerase chain reaction (PCR) (Linear Array HPV Genotyping Test, Roche Diagnostics, Mannheim, Germany). Results. Genotype 16 was the most prevalent HR-HPV in the three groups, 17.8% in the patients with normal cytology results, 22.3% in the LSIL group, and 60% in the HSIL group. Genotype 18 had a very low prevalence in all groups. Other HR-HPV genotypes such as genotype 31, genotype 58 and genotype 52 were found in significant numbers in HSIL patients. Discussion. Our data show that genotypes 16, 31, 58, and 52 are the most prevalent HR-HPV in cervical samples with severe intraepithelial lesion in Spain. There may be some geographical variation in prevalence of carcinogenic types, and it must be considered for designing diagnostic tests and vaccine

Advanced monitoring of rail breakage in double-track railway lines by means of PCA techniques

This work describes a classifier designed to identify rail breakages in double-track railway lines, completing the electronic equipment carried out by authors. The main objective of this proposal is to guarantee the integrity of tracks before the railway traffic starts working. In addition, it facilitates maintenance tasks providing information about possible breakages. The detection of breakages is based on the analysis of eight currents provided by the electronic equipment, one per rail, at the ends of the section (emitting and receiving nodes). The imbalance that occurs among the value of these currents implies that there is at least a breakage in the track section under analysis. This analysis is conducted according to three phases. The first one identifies whether there is a breakage, and, in that case, the damaged track is identified. The second phase provides information about which rail is broken (internal, external or both of them) in the previously identified track. Finally, if there is only one breakage, the third phase estimates its most likely zone along the track section. This situation is considered as a classification problem, and solved by means of the Principal Component Analysis technique. This means that a significant number of measurements is required for every breakage pattern (types of breakages) to be considered. Due to the difficulty of having real data, the proposal has been validated using an 8km-long double-track hardware simulator specially designed by the authors, with specific localizations for breakages

Replication of Human Norovirus in Mice after Antibiotic-Mediated Intestinal Bacteria Depletion

Human noroviruses (HuNoVs) are the main cause of acute gastroenteritis causing more than 50,000 deaths per year. Recent evidence shows that the gut microbiota plays a key role in enteric virus infectivity. In this context, we tested whether microbiota depletion or microbiota replacement with that of human individuals susceptible to HuNoVs infection could favor viral replication in mice. Four groups of mice (n = 5) were used, including a control group and three groups that were treated with antibiotics to eliminate the autochthonous intestinal microbiota. Two of the antibiotic-treated groups received fecal microbiota transplantation from a pool of feces from infants (age 1-3 months) or an auto-transplantation with mouse feces that obtained prior antibiotic treatment. The inoculation of the different mouse groups with a HuNoVs strain (GII.4 Sydney [P16] genotype) showed that the virus replicated more efficiently in animals only treated with antibiotics but not subject to microbiota transplantation. Viral replication in animals receiving fecal microbiota from newborn infants was intermediate, whereas virus excretion in feces from auto-transplanted mice was as low as in the control mice. The analysis of the fecal microbiota by 16S rDNA NGS showed deep variations in the composition in the different mice groups. Furthermore, differences were observed in the gene expression of relevant immunological mediators, such as IL4, CXCL15, IL13, TNFα and TLR2, at the small intestine. Our results suggest that microbiota depletion eliminates bacteria that restrict HuNoVs infectivity and that the mechanism(s) could involve immune mediators

The Nutritional Status of Long-Term Institutionalized Older Adults Is Associated with Functional Status, Physical Performance and Activity, and Frailty

Among older adults living in long-term nursing homes (LTNHs), maintaining an adequate functional status and independence is a challenge. Whilst a poor nutritional status is a potential risk factor for a decreased function in this population, its role is not fully understood. Here, using a transversal multicenter study of 105 older adults living in 13 LTNHs, we analyzed the associations between nutritional status, as measured by the Mini Nutritional Assessment (MNA), and the parameters of functional status, physical performance, physical activity, and frailty as well as comorbidity and body composition. The MNA scores were positively correlated with the Barthel Index, handgrip strength, Short Physical Performance Battery (SPPB) scores, absolute muscle power, and Assessment of Physical Activity in Frail Older People (APAFOP) scores and were negatively correlated with dynamic balance and frailty. In a multiple linear regression model controlling for gender and age, the APAFOP score (β = 0.386), BMI (β = 0.301), and Barthel Index (β = 0.220) explained 31% of the variance in the MNA score. Given the observed close relationship between the MNA score and functional status, physical performance and activity, and frailty, interventions should jointly target improvements in both the nutritional status and functional status of LTNH residents. Strategies designed and implemented by interdisciplinary professional teams may be the most successful in improving these parameters to lead to better health and quality of life.This research was funded by Diputación Foral de Gipuzkoa (ADINBERRI DG18/25) and the Professional Association of Nurses of Gipuzkoa (COEGI Nursing Research Grants 2019)

AEMET NWP Activities: 3rd ACCORD ASW

Póster presentado en: 3rd ACCORD ASW celebrado del 27 al 31 de marzo de 2023 en Tallin, Estonia

Evolutionary dynamics at the tumor edge reveal metabolic imaging biomarkers

Human cancers are biologically and morphologically heterogeneous. A variety of clonal populations emerge within these neoplasms and their interaction leads to complex spatiotemporal dynamics during tumor growth. We studied the reshaping of metabolic activity in human cancers by means of continuous and discrete mathematical models and matched the results to positron emission tomography (PET) imaging data. Our models revealed that the location of increasingly active proliferative cellular spots progressively drifted from the center of the tumor to the periphery, as a result of the competition between gradually more aggressive phenotypes. This computational finding led to the development of a metric, normalized distance from F-18-fluorodeoxyglucose (F-18-FDG) hotspot to centroid (NHOC), based on the separation from the location of the activity (proliferation) hotspot to the tumor centroid. The NHOC metric can be computed for patients using F-18-FDG PET-computed tomography (PET/CT) images where the voxel of maximum uptake (standardized uptake value [SUV]max) is taken as the activity hotspot. Two datasets of F-18-FDG PET/CT images were collected, one from 61 breast cancer patients and another from 161 non-small-cell lung cancer patients. In both cohorts, survival analyses were carried out for the NHOC and for other classical PET/CT-based biomarkers, finding that the former had a high prognostic value, outperforming the latter. In summary, our work offers additional insights into the evolutionary mechanisms behind tumor progression, provides a different PET/CT-based biomarker, and reveals that an activity hotspot closer to the tumor periphery is associated to a worst patient outcome